GS040153   Human Gene Therapy: Basic Science to Clinical Trial

Rajagopal, Ramesh (Coordinator) and Sastry, Jagannadha (Co-coordinator). Three semester hours. Spring annually. Prerequisite: a basic knowledge of cell biology and molecular biology will be expected; consent of instructor.

This course is intended to provide a state-of-the-art survey of the basic science and technology of gene therapy. Examples of both pre-clinical research and clinical trials will be presented. In addition, pertinent ethical, regulatory, intellectual property and industrial perspectives associated with the development of gene therapeutics will be examined. Classes will be presented by experts in the field from institutions both inside and outside the medical center. These investigators will discuss appropriate examples and data from their own studies, providing an excellent opportunity for participants to become familiar with potential future mentors.