Research Interests: Animal models of human disease; cancer biology; organotypic keratinocyte culture; comparative pathology; dermatopathology; cytopathology

The majority of my research involves comparative medicine, specifically animal models of human disease. My areas of expertise include; DNA sequencing, cross-hybridization strategies, cDNA microarray analysis and data mining, real-time RT-PCR, primary cell culture, organotypic keratinocyte culture, and flow cytometry. I have worked on animal species with limited genetic information and few perfected protocols. Consequently, I have become adept at modifying existing procedures to work effectively with non-traditional species. As a pathologist, I am frequently involved with immunohistochemistry and phenotyping cancers and cell lines.

As a faculty member with both service and research responsibilities, I do not have a laboratory, but work in collaboration with Drs. Feng Wang-Johanning and Gary Johanning. Tutorials in their laboratories could involve animal cancer models, immunotherapy, cell culture, gene expression, DNA methylation and other molecular biology techniques

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Barnhart KF, Credille KM, Ambrus S, Dunstan RW. Preservation of phenotype in an organotypic cell culture model of a recessive keratinization defect of Norfolk terriers. Exp Dermatol (in press, 2005)

Credille KM, Barnhart KF, Minor J, Venta PJ, Dunstan RW. Recessive epidermolytic hyperkeratosis associated with a keratin 10 donor splice site mutation in a family of Norfolk terrier dogs. Br J Dermatol (in press, 2005)

Barnhart KF, Credille KM, Ambrus S, Dunstan RW. Morphologic characterization of a heritable superficial epidermal keratin disorder in Norfolk terrier dogs. J Comp Pathol. 130:246-254, 2004