Lei Dong, Ph.D. 1995, The University of Texas at Houston Graduate School of Biomedical Sciences The University of Texas M. D. Anderson Cancer Center Department of Radiation Physics Contact Information Biographical Sketch

Research Interests:

• Treatment planning and optimization (IMRT and Proton therapy)
• Deformable image registration and its clinical applications
• Image-guided adaptive radiotherapy
• Radiation dose response analysis

My primary research interest is in image-guided radiation therapy, which involves the use of multi-modality imaging techniques for on-line or off-line treatment guidance or treatment plan adaptation to account for anatomical or biological changes during treatment course. We are developing novel image processing techniques, in particular, deformable image registration algorithms, to help various clinical activities that require mapping anatomical or functional changes in patients.  In addition, I am interested in patient’s geometric and dosimetric uncertainties during the course of radiotherapy treatment. With the recent development of highly conformal radiation treatment, such as the intensity modulated radiation therapy (IMRT) and proton therapy, these treatment-related uncertainties become one of the main issues. Our knowledge is lagging about the accuracy of radiation dose delivered to the patient in the presence of organ motion and how the tumor cells accurately responded to radiation doses. With the increasing use of novel imaging techniques in radiation therapy, there is an opportunity to improve the quality of radiotherapy.

A tutorial in my group would provide experience in image registration, treatment planning, and new technologies in image guidance.


Publications



Program Affiliation:

Program in Medical Physics