Carol J. Etzel, Ph.D. 1999, Southern Methodist University The University of Texas M. D. Anderson Cancer Center Department of Epidemiology Contact Information

Research Interests:

• Genetic linkage
• Statistical genetics
• Meta analysis
• Cancer epidemiology
• Genetic epidemiology
• Multiple imputation
• Risk assessment models
• Tree models
• Recursive partitioning
• Bayesian analyses

The research in my laboratory is directed at understanding genetic risk of disease. A strong interest in our lab is to construct risk models incorporating epidemiologic and genetic data to caracterize risk for lung cancer and to identify subgroups of individuals at highest risk who can be targeted for intensive intervention programs. Another interest in our lab is to develop meta-analytic methods to combine data across genetic linkage studies. Current studies in our lab focus on cancer risk model development, imputing missing genetic data to improve the risk models, as well as the development and testing of meta-analytic methods.

Depending on the student's interests, a tutorial in my laboratory would provide experience with statistical genetics and genetic epidemiology, genetic linkage methods, the development of risk models for diseases such as cancer or rheumatoid arthritis or development of meta-analytic methods to combine data across genome scan studies.


Selected Publications:

Etzel CJ, Mei L, Costello TJ. (2005) An Updated Meta-Analysis Approach for Genetic Linkage. BMC Genetic; 6(Suppl 1):S43.

Liu M, Scheurer ME, Bondy ML, Strom SS, Amos CI, Etzel CJ (2007) Extension of the cohort analysis for genetic epidemiology program to assess excess risk of cancer. In the Proceedings of the 2007 Joint Statistical Meetings. American Statistical Association; 2546-2550.

Spitz MR, Etzel CJ, Dong Q, Amos CI, Wei Q, Wu X, Hong WK (2008) An Expanded Risk Prediction Model of Lung Cancer. Cancer Prevention Research (in press).           

Etzel CJ, Kachroo S, Liu M, D’Amelio A, Dong Q, Cote ML, Wenzlaff AS, Hong WK, Greisinger AJ, Schwartz AG, Spitz MR (2008) Development and Validation of a lung cancer risk prediction model for African Americans. Cancer Prevention Research (in press).

Additional Publications

Program Affiliation:

Program in Biomathematics and Biostatistics