Thomas M. Guerrero, M.D., Ph.D.
1997, University of California-Los Angeles
1994, University of California-Los Angeles
The University of Texas M. D. Anderson Cancer Center
Department of Radiation Oncology
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Thomas M. Guerrero, M.D., Ph.D. 1997, University of California-Los Angeles The University of Texas M. D. Anderson Cancer Center |
My research focuses on medical imaging and radiation oncology. On the imaging side, my focus is on deformable image registration algorithms and applications. Using the optical flow algorithm (1) we have developed a new ventilation procedure from CT images which does not require contrast gases such as xenon (2). By matching tissue element from two breath-hold CT images, or across a 4D CT data set, we are able to calculate the difference in air volume and its distribution. On the radiation oncology side, the goal of this research is to develop imaging procedures that may be utilized in the radiotherapy treatment planning and to follow radiation injury to the lung after treatment. I plan to develop animal models of regional pulmonary biomechanical compliance in rodents and cardiac wall motion in dogs using CT and optical flow. With these I will investigate the temporal course and dose response to radiation and radio-protectors.
Students will be introduced to image processing and image analysis techniques. They will learn the basics of deformable image registration and participate in image based research projects. They will also have the opportunity to learn radiotherapy treatment planning.