Lisa M. Hollier, M.D., M.P.H. 1991, Tulane University School of Medicine UT-Houston Medical School Obstetrics, Gynecology and Reproductive Sciences Contact Information

Research Interests: Syphilis; herpes simplex virus type II; preterm labor; maternal immune response; prenatal diagnosis

My laboratory research interests involve maternal and perinatal infections with group B streptococcus and bacterial vaginosis. These studies have focused on the development of antibiotic resistance and the maternal immune response. Current research is focused on the role of inflammatory cytokines in the physiology of parturition in collaboration with Gailen D. Marshall, M.D., Ph.D., in the Division of Allergy and Immunology at the UT-Houston Medical School. Clinical research interests include maternal and perinatal infections with syphilis and herpes simplex type II. These studies have focused on the epidemiology of infection and on interventions to reduce vertical transmission.

Students in g-enetic counseling would gain experience in the design and execution of studies relating to a wide range of prenatal diagnosis issues. Diverse thesis ideas include: evaluation of patient perception of risk, new strategies to convey risk information to patients, use of antibiotics during pregnancy, and barriers to care among indigent women.
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Hollier LM, McIntire DD, Leveno KJ (1999) Outcome of twin pregnancies according to intrapair birthweight differences. Obstet Gynecol 94:1006-1010.

Hollier LM, Leveno KJ, Kelly MA, McIntire DD, Cunningham FG (2000) Maternal age and malformations in singleton births. Obstet Gynecol 96:701-706.

Tita AT, Hollier LM, Waller DK (2001) Seasonality in conception of births and influence on late initiation of prenatal care. Obstet Gynecol 97:976-981.

Hollier LM, Harstad TW, Sanchez PJ, Twickler DM, Wendel GD Jr (2001) Fetal syphilis: clinical and laboratory characteristics. Obstet Gynecol 97:947-953.

Scott LL, Hollier LM, McIntire D, Sanchez PJ, Jackson GL, Wendell GD jr (2001) Acyclovir suppression to prevent clinical recurrences at delivery after first episode genital herpes in pregnancy: an open-label trial. Infect Dis Obstet Gynecol 9:75-80.

Wendel GD, Sheffield JS, Hollier LM, et al (2002) Treatment of syphilis in pregnancy and prevention of congenital syphilis. Clinical Inf Dis 35:S200-209.

Scott LL, Hollier LM, McIntire D, Sanchez PJ, Jackson GL, Wendel GD Jr (2002) Acyclovir suppression to prevent clinical recurrences at delivery. Infect Dis Obstet Gynecol 10:71-78.

HollierLM, Hill J, Sheffield JS, Wendel GD Jr (2003) State laws regarding prenatal syphilis screening in the United States. Am J Obstet Gynecol 189:1178-1183.

Sheffield JS, Hollier LM, Hill JB, Stuart GS, Wendel GD Jr (2003) Acyclovir prophylaxis to prevent herpes simplex virus recurrence at delivery: a systematic review. Obstet Gynecol 102:1396-1403.

Mastrobattista J, Pschirrer ER, Hamrick MA, Glaser AM, Schumacher V, Shirkey BA, Wicklund CA, Hollier LM (2004) Humerus length evaluation in different ethnic groups. J Ultrasound Med 23:227-231.