Mien-Chie Hung, Ph.D. 1983, Brandeis University The University of Texas M. D. Anderson Cancer Center Department of Molecular and Cellular Oncology Contact Information

Research Interests:

• Molecular and cellular biology of oncogenes and antioncogenes
• Gene expression and regulation
• Growth factor receptors
• Signaling transduction and cancer biology

This laboratory is studying the role of oncogenes (cancer-inducing) and antioncogenes (tumor suppressor) in the carcinogensis from the aspects of molecular and cellular biology. We are especially interested in those oncogenes which code for growth factor receptors, and transcription factors. We are also interested in signaling transduction and gene regulation that control cell growth and tumorigenesis. In addition, using tumor suppressor genes of targeting oncogenes, we also develop gene therapy protocol for breast, head and neck, lung, ovarian, pancreatic, and prostate cancers.

A tutorial in this laboratory would provide experience in techniques for gene expression, molecular cloning, growth factor and receptor interaction. Also provided is a training for independent thinking on designing experiments for tackling scientific problems.

Selected Publications

Program Affiliations:

Program in Cancer Biology

Program in Molecular Carcinogenesis

Program in Molecular Pathology

Program in Virology and Gene Therapy