Research Interests:

• Cancer vaccines
• Cancer immunotherapy
• Cancer immunology
• T cell biology

The research in my laboratory is directed at understanding and promoting the immune response to cancer in an effort to develop and improve cancer treatments. We focus on melanoma using a unique mouse model of tumor-specific T cells that we developed. We are especially interested in increasing the anti-tumor effect of tumor-specific T cells by vaccines or adoptive T cell transfer.

Depending on the student’s interests, a tutorial in my laboratory would provide experience with mouse models of melanoma, following vaccination-induced immune responses in vivo, and analysis of tumor-specific T cell function. We are also working on immunotherapy of human tumors in mice and on in vivo bioluminescent imaging of tumor growth and T cell migration.

Publications

Program Affiliation:

Program in Immunology