Eva M. Sevick, Ph.D. 1989, Carnegie Mellon University The University of Texas Health Science Center at Houston Institute of Molecular Medicine Center for Molecular Imaging Contact Information Biographical Sketch

Research Interests:

• Molecular imaging
• Near-infrared light
• Cancer detection
• Small animal models of cancer
• Gene expression reporters and probes
• Fluorescence
• Clinical translation

Research projects in the Center for Molecular Imaging focus upon the development and/or use of imaging, imaging agents, and gene expression reporters to understand human disease in small animal models.

A tutorial in my laboratory would provide experience in near-infrared fluorescent contrast agents, near-infrared imaging and tomography, PET/CT, hybrid imaging modalities, validation of molecular imaging agents, use of molecular imaging to understand molecular genetics, clinical translation.

Selected Publications:

Sevick-Muraca EM, Sharma R, Rasmussen JC, Marshall MV, Wendt JA, Pham HQ, Bonefas E, Houston JP, Sampath L, Adams KE, Blanchard DK, Fisher RE, Chiang S, Elledge R, Mawad ME (2008) Imaging of lymph flow in breast cancer patients after microdose administration of a near-infrared fluorophore. Radiology, 246:734-741.

Sevick-Muraca EM, Rasmussen JC (2008) Molecular Imaging with Optics: A Primer and a Case for Near-Infrared Fluorescence Techniques in Personalized Medicine. J Biomedical Optics, 13(4), 041303.

Sampath L, Kwon S, Ke S, Wang W, Schiff R, Mawad ME, Sevick-Muraca EM (2007) Dual labeled trastuzamab-based imaging agent for the detection of human epidermal growth factor receptor-2 (HER2) overexpression in breast cancer. J Nuclear Medicine, 48:1501-1510.

Lee JH, Joshi A, Sevick-Muraca EM (2008) Fast intersections on nested tetrahedrons (FINT): An algorithm for adaptive finite element based distributed parameter estimation. J Computational Physics, 227:5778-5798.

Publications